Long-form research pillars

Research Pillars

Deep dives into the major peptide research classes — mechanism, canonical trial data, head-to-head comparisons, protocol design, and the products we stock for each pillar. Longer and broader than individual blog posts; narrower than the glossary.

Metabolic Research Pillar

GLP-1 Agonists: The Research Class Rewriting Metabolic Biology

Comprehensive research hub on GLP-1 receptor agonists — Semaglutide, Tirzepatide, Retatrutide. Mechanism, trial data, head-to-head comparisons, and reconstitution protocols.

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Regenerative Research Pillar

Tissue Repair Peptides: Angiogenesis, Cell Migration, and the Repair Cascade

Research hub on tissue-repair peptides — BPC-157, TB-500 (Thymosin Beta-4), and complementary compounds. Mechanism, local-vs-systemic administration, stacking, and protocol design.

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Dermatological Research Pillar

Beauty & Skin Biology: Copper Peptides, Collagen Signaling, and Dermal Research

Research hub on peptides studied in dermatology and cosmeceutical research — GHK-Cu copper peptide, gene-expression modulation, collagen synthesis pathways.

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Anabolic Research Pillar

Growth Hormone Secretagogues: Pulsatile GH, Body Composition, and the GHRH/GHRP Axis

Research hub on GH-secretagogue peptides — CJC-1295, Ipamorelin, Sermorelin, Tesamorelin, Hexarelin. Pulsatile vs continuous GH release, GHRH-analog vs GHRP-analog mechanism, stacking, and protocol design.

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Cognitive Research Pillar

Cognitive Peptides: BDNF, Anxiolysis, and Neuroprotection Without Sedation

Research hub on cognitive and neuroprotective peptides — Selank, Semax, Cerebrolysin. BDNF/NGF upregulation, GABAergic anxiolysis without sedation, neurorestoration mechanisms, and protocol design.

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Longevity Research Pillar

Cellular Longevity: Telomere Biology, Mitochondrial Peptides, and the NAD+ Cofactor

Research hub on cellular longevity peptides — Epithalon, MOTS-c, NAD+. Telomerase activation, mitochondrial-derived peptide signaling, sirtuin-cofactor biology, and the hallmarks-of-aging framework.

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Research peptides referenced across these pillars

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Skin HealthBestseller

Thymosin Beta-4 10mg

FourNines

Thymosin Beta-4 (TB-500) — 43-amino-acid actin-sequestering peptide studied for systemic soft-tissue repair and angiogenesis.

PT-141 10mg

Supreme Biologics

Bremelanotide — a cyclic melanocortin peptide studied for its effects on the central MC3R/MC4R pathway.

Selank 5mg

Supreme Biologics

Synthetic heptapeptide anxiolytic analog of tuftsin — studied for GABAergic modulation without sedation.

Semax 5mg

Supreme Biologics

Synthetic heptapeptide analog of ACTH(4-10) — studied for BDNF induction and cognitive effects.

Weight LossBestseller

Retatrutide 5mg

Supreme Biologics

Triple GIP/GLP-1/glucagon receptor agonist — next-generation incretin under active clinical investigation.

Skin HealthBestseller

BPC-157 5mg

FourNines

Body Protection Compound — a 15-amino-acid gastric-derived peptide studied for tendon, ligament, and mucosal repair.

Skin HealthBestseller

GHK-Cu 50mg

FourNines

Copper-binding tripeptide (Gly-His-Lys) — naturally occurring peptide studied for collagen synthesis, hair follicle biology, and dermal regeneration.

Muscle GrowthBestseller

CJC-1295 (no DAC) 5mg

FourNines

Modified GRF 1-29 — a short-acting synthetic GHRH analog without the albumin-binding DAC linker.

Muscle GrowthBestseller

Ipamorelin 5mg

FourNines

Selective growth hormone secretagogue — a clean GHRP analog with minimal cortisol or prolactin elevation.

Epithalon 50mg

FourNines

Ala-Glu-Asp-Gly tetrapeptide derived from pineal-gland polypeptide extracts — studied for telomerase upregulation and circadian normalization.

Research pillars summarize the current state of peptide research by compound class. All content is reviewed against primary literature — see our editorial standards. Compounds are chemical reagents for laboratory analysis only.