2.5 mg × 8 vial · Lyophilized powder
Mitochondrial-derived 16-amino-acid peptide studied for metabolic regulation and AMPK activation. Format: Supreme Biologics dual-chamber cartridges (glass, no needle), for use with the Supreme Biologics dual-chamber injector (sold separately). Ships dry: the diluent chamber is empty, add bacteriostatic water (not included) before use. Custom box combinations are available on request via LINE. For research use only.
Relative emphasis across the research domains this compound is most studied for.
Sourced direct from a vetted GMP-aligned manufacturer. No re-labels, no middle layers.
View brandDetailed compound information
MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA region. Research models show it translocates to the nucleus under metabolic stress and regulates nuclear gene expression — a rare example of mitochondrial-to-nuclear retrograde signaling. Downstream effects include AMPK pathway activation, improved insulin sensitivity, and enhanced cellular energy metabolism.
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Reference material & peer-reviewed citations
Research peptides are chemical reagents for laboratory analysis. Regulations vary by jurisdiction — it is the buyer's responsibility to ensure compliance with local laws. See our Terms & Conditions page for the full regulatory framework across the EU, UK, US, Switzerland, Thailand, and other major markets.
Lyophilized (unreconstituted) peptides should be stored at -20°C for long-term storage or 2-8°C (refrigerated) for short-term use. Once reconstituted with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles — aliquot into smaller portions if needed.
For laboratory research use only. Not for human consumption, diagnosis, treatment, prevention, or in-vivo administration. By purchasing you confirm you are a qualified researcher or institution.
Supplied as a box of Supreme Biologics dual-chamber cartridges (glass, no needle). The peptide chamber contains lyophilized powder; the diluent chamber ships empty, so add bacteriostatic water (not included) before use. For use with the Supreme Biologics dual-chamber injector (sold separately). Custom box combinations are available on request via LINE. For research use only.
Gently inject bacteriostatic water (bacteriostatic water) along the inside wall of the vial — do not spray directly onto the powder. Let it dissolve naturally or gently swirl. Never shake vigorously. Standard reconstitution: add the desired volume of bacteriostatic water based on your concentration needs. For example, 5mg peptide + 2.5ml bacteriostatic water = 2mg/ml concentration.
Yes. Every batch undergoes independent third-party HPLC (High-Performance Liquid Chromatography) and mass spectrometry analysis. We provide a Certificate of Analysis (COA) for each product, verifying identity, purity (≥99%), and the absence of contaminants. COA documents are available for download on each product page.
Yes. We offer temperature-controlled shipping to most EU and Asian countries. Standard EU delivery is 24-48 hours. International orders are shipped in discreet, professional packaging with cold-chain protection where required. Customs documentation and regulatory paperwork are provided as needed.
We currently operate on an inquiry-based ordering system. Submit your order through checkout and our team will contact you within 24 hours to confirm details and arrange payment. We are working on integrating direct payment options for a seamless experience.
A Physician's Endorsement
Quality assurance isn't a marketing claim — it's a daily decision. I choose LifeSpanSupply because every batch is independently HPLC-verified to 99% purity, fully traceable, and held to the safety standards my patients deserve.
Dr. Pichaya Sangaunmu
M.D. · Wellness · Beauty · Longevity
Three curated paths into the research literature on this compound.
