https://lifespansupply.com Pharmaceutical-grade research peptides. HPLC-verified purity. prod_01KNS3NTBK0TAPCMVGREAJ7GXV BPC-157 5mg — Supreme Biologics BPC-157 is a synthetic pentadecapeptide derived from a human gastric protective protein. Research models show it drives angiogenesis via VEGFR2 signaling and modulates nitric oxide synthesis, accelerating soft-tissue repair at the injury site. Unlike systemic healing peptides, BPC-157 shows strongest effects when delivered locally near the lesion — a property that has made it a widely cited research tool across tendon, ligament, and gastrointestinal models. Research Applications • Tendon & ligament repair — promotes collagen deposition and capillary formation in preclinical tendon-injury models. • Gut mucosal protection — reverses NSAID-induced lesions and supports intestinal barrier integrity in animal studies. • Vascular & endothelial studies — used to probe VEGFR2 signaling and nitric oxide cross-talk. • Post-surgical recovery models — investigated alongside TB-500 and GHK-Cu for combined soft-tissue repair protocols. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water along the interior wall (never directly into the powder). Swirl gently, do not shake. Yields 2.5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 250 mcg. https://lifespansupply.com/product/bpc-157-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-bpc-157-5mg-supreme-biologics-slide0-6ea497e61c.png in stock 104.00 USD Supreme Biologics new no Skin & Tissue prod_01KNS3NTBKF1D8JEACBACJYSP2 Ipamorelin 5mg — Supreme Biologics Ipamorelin is a pentapeptide ghrelin-receptor (GHS-R1a) agonist that triggers pulsatile GH release from pituitary somatotrophs. Its defining property is receptor selectivity — at therapeutic research doses it produces minimal cortisol, prolactin, or ACTH elevation, distinguishing it from earlier GHRPs like GHRP-6 or GHRP-2. This makes it the cleanest GHRP for extended-cycle research protocols. Research Applications • GH/IGF-1 axis studies — pulsatile release without confounding hormone spikes. • Recovery & muscle protein synthesis — evening-dose protocols alongside GHRH analogs. • Lean-mass preservation — caloric-deficit research models. • Paired-peptide protocols — synergistic amplification when stacked with CJC-1295. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 250 mcg per pulse. https://lifespansupply.com/product/ipamorelin-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-ipamorelin-5mg-supreme-biologics-slide0-1fe8809398.png in stock 97.00 USD Supreme Biologics new no Growth Hormone prod_01KNS3NTBKTKSS55CQ8K4MCE7V GHK-Cu 50mg — Calyssee GHK-Cu is a naturally-occurring copper tripeptide first isolated from human plasma. Research models show it delivers Cu²⁺ ions to copper-dependent enzymes (lysyl oxidase chief among them) that crosslink collagen and elastin fibers, producing denser, more resilient extracellular matrix. It modulates gene expression broadly — downregulating NF-κB inflammatory programs while upregulating antioxidant and repair pathways. Reconstituted solution is characteristically blue (copper salt in solution, not contamination). Research Applications • Dermal remodeling research — collagen/elastin synthesis and wound contraction studies. • Hair follicle biology — dermal papilla cell proliferation and anagen induction. • Gene expression studies — transcriptional modulation of repair and anti-inflammatory programs. • Post-procedure dermal research — recovery following laser, microneedling, and chemical peel models. Preparation For the 50mg vial: reconstitute with 5mL bacteriostatic water → 10 mg/mL. Solution will be blue — this is normal copper salt coloration. On a U-100 insulin syringe, 10 IU = 0.1 mL = 1 mg. Topical preparations dilute to 0.1–0.5% in sterile saline. Do NOT freeze reconstituted solutions — copper salts drop out of solution. https://lifespansupply.com/product/ghk-cu-50mg-calyssee https://api.lifespansupply.com/static/2026-04-18-ghk-cu-50mg-calyssee-slide0-10ac551dac.png in stock 91.00 USD Calyssee new no Skin & Tissue prod_01KNS3NTBKYWF4HG31DTBT21KM Thymosin Beta-4 10mg — FourNines Thymosin Beta-4 is a ubiquitous 43-amino-acid protein that binds monomeric G-actin and regulates cytoskeletal dynamics. Research models show it drives cell migration toward injury sites, upregulates VEGF-mediated angiogenesis, and modulates inflammatory cytokine profiles. Unlike BPC-157, which works best injected near the injury, TB4 operates systemically — remote injection delivers comparable effects across multiple tissue compartments. Research Applications • Muscle & tendon repair — accelerates regeneration in preclinical soft-tissue injury models. • Angiogenesis studies — standard research tool for VEGF pathway investigation. • Cardiac recovery models — studied for myocardial repair following ischemic injury. • Corneal & dermal wound healing — promotes re-epithelialization in multiple tissue types. Preparation Reconstitute the 10mg vial with 2mL bacteriostatic water slowly along the interior wall. Yields 5 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 1 mg. https://lifespansupply.com/product/thymosin-beta-4-10mg-fournines https://api.lifespansupply.com/static/2026-04-18-thymosin-beta-4-10mg-fournines-slide0-0c342d1327.png in stock 182.00 USD FourNines new no Skin & Tissue prod_01KPC0B3FYR2YTSCAD8V8N615F MOTS-c 10mg — Supreme Biologics MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA region. Research models show it translocates to the nucleus under metabolic stress and regulates nuclear gene expression — a rare example of mitochondrial-to-nuclear retrograde signaling. Downstream effects include AMPK pathway activation, improved insulin sensitivity, and enhanced cellular energy metabolism. Research Applications • Metabolic research — insulin sensitivity and glucose uptake models. • Exercise physiology — AMPK/PGC-1α pathway investigation. • Mitochondrial biogenesis studies — preclinical models of age-related metabolic decline. • Body composition research — combined fat-loss and lean-mass protocols. Preparation Reconstitute the 10mg vial with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 1 mg. https://lifespansupply.com/product/mots-c-10mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-mots-c-10mg-supreme-biologics-slide0-7336611ced.png in stock 91.00 USD Supreme Biologics new no Cellular Repair prod_01KPGYPJPMFBZGZZVNPTHQY377 Thymosin Beta-4 10mg — Supreme Biologics Thymosin Beta-4 is a ubiquitous 43-amino-acid protein that binds monomeric G-actin and regulates cytoskeletal dynamics. Research models show it drives cell migration toward injury sites, upregulates VEGF-mediated angiogenesis, and modulates inflammatory cytokine profiles. Unlike BPC-157, which works best injected near the injury, TB4 operates systemically — remote injection delivers comparable effects across multiple tissue compartments. Research Applications • Muscle & tendon repair — accelerates regeneration in preclinical soft-tissue injury models. • Angiogenesis studies — standard research tool for VEGF pathway investigation. • Cardiac recovery models — studied for myocardial repair following ischemic injury. • Corneal & dermal wound healing — promotes re-epithelialization in multiple tissue types. Preparation Reconstitute the 10mg vial with 2mL bacteriostatic water slowly along the interior wall. Yields 5 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 1 mg. https://lifespansupply.com/product/thymosin-beta-4-10mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-thymosin-beta-4-10mg-supreme-biologics-slide0-e5f9f2198b.png in stock 146.00 USD Supreme Biologics new no Skin & Tissue prod_01KPGYPK2QDEZ3GG1XYZ2HCMF9 PT-141 10mg — Supreme Biologics PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-MSH that acts primarily at melanocortin receptors MC3R and MC4R. Research models show it modulates central signaling pathways associated with pigmentation, appetite regulation, and autonomic response — distinct from peripherally-acting peptides. Initial development was for sunless tanning; later research focused on CNS-mediated endpoints. Research Applications • Melanocortin pathway research — MC3R/MC4R agonism studies. • Central nervous system signaling — probe for hypothalamic pathways. • Pigmentation biology — MSH-pathway activation studies. • Autonomic response modeling — investigation of sympathetic tone and cardiovascular responses. Preparation For the 10mg vial: reconstitute with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 500 mcg. For nasal spray presentations the device is pre-calibrated — follow the included dosing card. https://lifespansupply.com/product/pt-141-10mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-pt-141-10mg-supreme-biologics-slide0-b6077e86f8.png in stock 76.00 USD Supreme Biologics new no Beauty prod_01KPGYPKBH8N41AJ63Z4DFN8J2 CJC-1295 (no DAC) 5mg — Supreme Biologics CJC-1295 (no DAC), also called Modified GRF 1-29, is a synthetic GHRH analog stabilized against dipeptidyl peptidase-IV cleavage. Without the DAC linker, its plasma half-life is approximately 30 minutes — meaning each injection produces a discrete GH pulse rather than a sustained elevation. Research models use it to study acute GH axis responses, and it is often paired with a GHRP such as Ipamorelin, which triggers pulses against the elevated GHRH tone. Research Applications • GH axis research — pulsatile GH release studies paired with GHRP compounds. • Anabolic signaling models — IGF-1 response investigation. • Recovery & sleep architecture — evening-pulse protocols in preclinical models. • Lean body composition studies — paired with Ipamorelin for synergistic GH secretion. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 4 IU = 0.04 mL = 100 mcg per pulse. https://lifespansupply.com/product/cjc-1295-no-dac-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-cjc-1295-no-dac-5mg-supreme-biologics-slide0-7a76d0ab65.png in stock 97.00 USD Supreme Biologics new no Growth Hormone prod_01KPGYPM198ASF050S1F7X5XSQ Selank 5mg — Supreme Biologics Selank is a synthetic heptapeptide developed from the endogenous immunomodulator tuftsin. Research models show it modulates the GABAergic system and influences BDNF expression in specific hippocampal regions. Unlike benzodiazepines, animal studies indicate its anxiolytic profile does not produce sedation, cognitive impairment, or tolerance, making it a notable investigational tool for stress-response research. Research Applications • Anxiolytic pathway research — GABA-A receptor modulation without sedation endpoints. • Neurotrophic factor studies — BDNF/nerve growth factor expression models. • Stress-response investigations — HPA axis regulation in chronic-stress models. • Cognitive performance models — attention and working memory under stress. Preparation Reconstitute the 5mg vial with 1mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 5 IU = 0.05 mL = 250 mcg. Nasal spray presentation (if selected) is pre-calibrated per-actuation. https://lifespansupply.com/product/selank-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-selank-5mg-supreme-biologics-slide0-5a6206011a.png in stock 182.00 USD Supreme Biologics new no Cognitive prod_01KPGYPMA0G9CVQGF4P5D2QJB4 Semax 5mg — Supreme Biologics Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Research models show it rapidly upregulates BDNF and NGF in the hippocampus and cortex, and modulates enkephalin degradation. It is used experimentally in Russia for stroke recovery and cognitive research endpoints, and remains a standard investigational tool for neurotrophic pathway research. Research Applications • Neurotrophic factor induction — BDNF/NGF upregulation studies. • Cognitive performance models — memory consolidation and learning paradigms. • Neuroprotection research — ischemia and hypoxia preclinical models. • Mood/stress regulation — melanocortin-adjacent signaling investigations. Preparation Reconstitute the 5mg vial with 1mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 6 IU = 0.06 mL = 300 mcg. Nasal spray presentation (if selected) is pre-calibrated per-actuation. https://lifespansupply.com/product/semax-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-semax-5mg-supreme-biologics-slide0-946d5f5217.png in stock 273.00 USD Supreme Biologics new no Cognitive prod_01KPGYPMM8JCAYX3PGZNGMJ0XQ Retatrutide 5mg — Supreme Biologics Retatrutide is a synthetic peptide agonist at three receptors simultaneously: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. Research models demonstrate substantial reductions in body weight and glycemic parameters in obesity and type-2 diabetes investigations, exceeding the effects of dual GIP/GLP-1 agonists. The glucagon component is thought to contribute additional hepatic and energy-expenditure effects. Research Applications • Weight management research — preclinical and translational obesity models. • Glycemic control — GIP/GLP-1 co-agonist pathway studies. • Hepatic lipid metabolism — glucagon-receptor contribution investigations. • Cardiometabolic risk models — integrated metabolic endpoint research. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 8 IU = 0.08 mL = 200 mcg as a starter dose per research protocols. https://lifespansupply.com/product/retatrutide-5mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-retatrutide-5mg-supreme-biologics-slide0-2a749913f8.png in stock 304.00 USD Supreme Biologics new no GLP-1 Agonists prod_01KPGYPMX8NZTVYYPA8HSHF72T NAD+ 100mg — Supreme Biologics NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme present in every living cell, central to redox reactions and sirtuin enzyme activity. Research shows cellular NAD+ levels decline with age and correlate with mitochondrial dysfunction. Direct NAD+ administration in research models aims to restore intracellular stores and activate SIRT1/SIRT3-mediated longevity pathways, supporting DNA repair and metabolic regulation. Research Applications • Longevity research — sirtuin activation and age-related decline models. • Mitochondrial function — oxidative phosphorylation and ATP production studies. • DNA repair pathways — PARP and sirtuin NAD-consuming enzyme research. • Neurological models — cognitive decline and neuroprotection studies. Preparation For the 100mg vial: reconstitute with 2mL bacteriostatic water → 50 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 10 mg. Slow injection (over 10+ minutes) is standard protocol to minimize flushing. https://lifespansupply.com/product/nad-plus-100mg-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-nad-plus-100mg-supreme-biologics-slide0-ba191bff98.png in stock 304.00 USD Supreme Biologics new no Cellular Repair prod_01KPGYPN5V7K5QV1T5WBHX58VE PT-141 150mg Nasal Spray — Supreme Biologics PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-MSH that acts primarily at melanocortin receptors MC3R and MC4R. Research models show it modulates central signaling pathways associated with pigmentation, appetite regulation, and autonomic response — distinct from peripherally-acting peptides. Initial development was for sunless tanning; later research focused on CNS-mediated endpoints. Research Applications • Melanocortin pathway research — MC3R/MC4R agonism studies. • Central nervous system signaling — probe for hypothalamic pathways. • Pigmentation biology — MSH-pathway activation studies. • Autonomic response modeling — investigation of sympathetic tone and cardiovascular responses. Preparation For the 10mg vial: reconstitute with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 500 mcg. For nasal spray presentations the device is pre-calibrated — follow the included dosing card. https://lifespansupply.com/product/pt-141-150mg-nasal-spray-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-pt-141-150mg-nasal-spray-supreme-biologics-slide0-cd3c4d75b9.png in stock 200.00 USD Supreme Biologics new no Beauty prod_01KPGYPNDXND3WP9EY0N9MH8GB Semax 45mg Nasal Spray — Supreme Biologics Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Research models show it rapidly upregulates BDNF and NGF in the hippocampus and cortex, and modulates enkephalin degradation. It is used experimentally in Russia for stroke recovery and cognitive research endpoints, and remains a standard investigational tool for neurotrophic pathway research. Research Applications • Neurotrophic factor induction — BDNF/NGF upregulation studies. • Cognitive performance models — memory consolidation and learning paradigms. • Neuroprotection research — ischemia and hypoxia preclinical models. • Mood/stress regulation — melanocortin-adjacent signaling investigations. Preparation Reconstitute the 5mg vial with 1mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 6 IU = 0.06 mL = 300 mcg. Nasal spray presentation (if selected) is pre-calibrated per-actuation. https://lifespansupply.com/product/semax-45mg-nasal-spray-supreme-biologics https://api.lifespansupply.com/static/2026-04-18-semax-45mg-nasal-spray-supreme-biologics-slide0-ac97269838.png in stock 388.00 USD Supreme Biologics new no Cognitive prod_01KPGYRE4BP57YQHJ77JPQDH0T BPC-157 5mg — FourNines BPC-157 is a synthetic pentadecapeptide derived from a human gastric protective protein. Research models show it drives angiogenesis via VEGFR2 signaling and modulates nitric oxide synthesis, accelerating soft-tissue repair at the injury site. Unlike systemic healing peptides, BPC-157 shows strongest effects when delivered locally near the lesion — a property that has made it a widely cited research tool across tendon, ligament, and gastrointestinal models. Research Applications • Tendon & ligament repair — promotes collagen deposition and capillary formation in preclinical tendon-injury models. • Gut mucosal protection — reverses NSAID-induced lesions and supports intestinal barrier integrity in animal studies. • Vascular & endothelial studies — used to probe VEGFR2 signaling and nitric oxide cross-talk. • Post-surgical recovery models — investigated alongside TB-500 and GHK-Cu for combined soft-tissue repair protocols. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water along the interior wall (never directly into the powder). Swirl gently, do not shake. Yields 2.5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 250 mcg. https://lifespansupply.com/product/bpc-157-5mg-fournines https://api.lifespansupply.com/static/2026-04-18-bpc-157-5mg-fournines-slide0-50033fbcec.png in stock 137.00 USD FourNines new no Skin & Tissue prod_01KPGYRETT6ZMPJ9QRY54MC8H0 GHK-Cu 50mg — FourNines GHK-Cu is a naturally-occurring copper tripeptide first isolated from human plasma. Research models show it delivers Cu²⁺ ions to copper-dependent enzymes (lysyl oxidase chief among them) that crosslink collagen and elastin fibers, producing denser, more resilient extracellular matrix. It modulates gene expression broadly — downregulating NF-κB inflammatory programs while upregulating antioxidant and repair pathways. Reconstituted solution is characteristically blue (copper salt in solution, not contamination). Research Applications • Dermal remodeling research — collagen/elastin synthesis and wound contraction studies. • Hair follicle biology — dermal papilla cell proliferation and anagen induction. • Gene expression studies — transcriptional modulation of repair and anti-inflammatory programs. • Post-procedure dermal research — recovery following laser, microneedling, and chemical peel models. Preparation For the 50mg vial: reconstitute with 5mL bacteriostatic water → 10 mg/mL. Solution will be blue — this is normal copper salt coloration. On a U-100 insulin syringe, 10 IU = 0.1 mL = 1 mg. Topical preparations dilute to 0.1–0.5% in sterile saline. Do NOT freeze reconstituted solutions — copper salts drop out of solution. https://lifespansupply.com/product/ghk-cu-50mg-fournines https://api.lifespansupply.com/static/2026-04-18-ghk-cu-50mg-fournines-slide0-187d60b157.png in stock 137.00 USD FourNines new no Skin & Tissue prod_01KPGYRF4HKK6BNSEF9D0X2CWS CJC-1295 (no DAC) 5mg — FourNines CJC-1295 (no DAC), also called Modified GRF 1-29, is a synthetic GHRH analog stabilized against dipeptidyl peptidase-IV cleavage. Without the DAC linker, its plasma half-life is approximately 30 minutes — meaning each injection produces a discrete GH pulse rather than a sustained elevation. Research models use it to study acute GH axis responses, and it is often paired with a GHRP such as Ipamorelin, which triggers pulses against the elevated GHRH tone. Research Applications • GH axis research — pulsatile GH release studies paired with GHRP compounds. • Anabolic signaling models — IGF-1 response investigation. • Recovery & sleep architecture — evening-pulse protocols in preclinical models. • Lean body composition studies — paired with Ipamorelin for synergistic GH secretion. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 4 IU = 0.04 mL = 100 mcg per pulse. https://lifespansupply.com/product/cjc-1295-no-dac-5mg-fournines https://api.lifespansupply.com/static/2026-04-19-cjc-1295-no-dac-5mg-fournines-slide0-613196f011.png in stock 122.00 USD FourNines new no Growth Hormone prod_01KPGYRFF6K2HFZS8H1HTAT6H9 Ipamorelin 5mg — FourNines Ipamorelin is a pentapeptide ghrelin-receptor (GHS-R1a) agonist that triggers pulsatile GH release from pituitary somatotrophs. Its defining property is receptor selectivity — at therapeutic research doses it produces minimal cortisol, prolactin, or ACTH elevation, distinguishing it from earlier GHRPs like GHRP-6 or GHRP-2. This makes it the cleanest GHRP for extended-cycle research protocols. Research Applications • GH/IGF-1 axis studies — pulsatile release without confounding hormone spikes. • Recovery & muscle protein synthesis — evening-dose protocols alongside GHRH analogs. • Lean-mass preservation — caloric-deficit research models. • Paired-peptide protocols — synergistic amplification when stacked with CJC-1295. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 250 mcg per pulse. https://lifespansupply.com/product/ipamorelin-5mg-fournines https://api.lifespansupply.com/static/2026-04-18-ipamorelin-5mg-fournines-slide0-056ec1d79f.png in stock 122.00 USD FourNines new no Growth Hormone prod_01KPGYRFVEH861AJK4PQ0SAJV9 DSIP 5mg — FourNines DSIP is an endogenous nonapeptide first isolated from rabbit cerebral venous blood during electrically-induced sleep. Research models show it modulates slow-wave (delta) sleep architecture, influences HPA axis regulation, and demonstrates anti-nociceptive and stress-buffering properties. Unlike GABAergic sleep agents, its mechanism is not fully characterized but involves modulation of corticotropin release. Research Applications • Sleep architecture research — slow-wave (delta) sleep induction studies. • HPA axis regulation — stress-response and cortisol modulation models. • Chronobiology studies — circadian entrainment investigations. • Anti-nociception research — pain-tolerance and opioid-sparing models. Preparation Reconstitute the 5mg vial with 1mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 2 IU = 0.02 mL = 100 mcg. Pre-bed administration is standard protocol. https://lifespansupply.com/product/dsip-5mg-fournines https://api.lifespansupply.com/static/2026-04-18-dsip-5mg-fournines-slide0-8efd51ebda.png in stock 107.00 USD FourNines new no Cellular Repair prod_01KPGYRG6BWJX8W71JCGKDQ672 Epithalon 50mg — FourNines Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on epithalamin, a bovine pineal-gland polypeptide fraction. Research from Khavinson's group at the Saint Petersburg Institute of Bioregulation and Gerontology has examined its effects on telomerase expression, melatonin-axis function, and extended lifespan in animal models. Human studies most consistently report sleep architecture improvements, particularly enhanced delta-sleep phases, within the first several days of pulsed dosing. Research Applications • Telomerase & longevity research — hTERT upregulation and cellular senescence models. • Circadian & sleep research — melatonin axis modulation and delta-sleep studies. • Oxidative stress models — antioxidant gene expression investigations. • Immunosenescence research — thymic involution and T-cell aging models. Preparation For the 50mg vial: reconstitute with 5mL bacteriostatic water → 10 mg/mL. On a U-100 insulin syringe, 5 IU = 0.05 mL = 5 mg. Classic Khavinson protocol is 10-day or 20-day pulses, 2–3× per year. https://lifespansupply.com/product/epithalon-50mg-fournines https://api.lifespansupply.com/static/2026-04-18-epithalon-50mg-fournines-slide0-e84bffc3a8.png in stock 304.00 USD FourNines new no Cellular Repair prod_01KPGYRGHYYMWK5YN2FZ9Q1NBN MOTS-c 10mg — FourNines MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA region. Research models show it translocates to the nucleus under metabolic stress and regulates nuclear gene expression — a rare example of mitochondrial-to-nuclear retrograde signaling. Downstream effects include AMPK pathway activation, improved insulin sensitivity, and enhanced cellular energy metabolism. Research Applications • Metabolic research — insulin sensitivity and glucose uptake models. • Exercise physiology — AMPK/PGC-1α pathway investigation. • Mitochondrial biogenesis studies — preclinical models of age-related metabolic decline. • Body composition research — combined fat-loss and lean-mass protocols. Preparation Reconstitute the 10mg vial with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 1 mg. https://lifespansupply.com/product/mots-c-10mg-fournines https://api.lifespansupply.com/static/2026-04-18-mots-c-10mg-fournines-slide0-343a9fb222.png in stock 122.00 USD FourNines new no Cellular Repair prod_01KPGYRGTEF5H54KRF0D8D1721 NAD+ 100mg — FourNines NAD+ (nicotinamide adenine dinucleotide) is a fundamental coenzyme present in every living cell, central to redox reactions and sirtuin enzyme activity. Research shows cellular NAD+ levels decline with age and correlate with mitochondrial dysfunction. Direct NAD+ administration in research models aims to restore intracellular stores and activate SIRT1/SIRT3-mediated longevity pathways, supporting DNA repair and metabolic regulation. Research Applications • Longevity research — sirtuin activation and age-related decline models. • Mitochondrial function — oxidative phosphorylation and ATP production studies. • DNA repair pathways — PARP and sirtuin NAD-consuming enzyme research. • Neurological models — cognitive decline and neuroprotection studies. Preparation For the 100mg vial: reconstitute with 2mL bacteriostatic water → 50 mg/mL. On a U-100 insulin syringe, 20 IU = 0.2 mL = 10 mg. Slow injection (over 10+ minutes) is standard protocol to minimize flushing. https://lifespansupply.com/product/nad-plus-100mg-fournines https://api.lifespansupply.com/static/2026-04-18-nad-plus-100mg-fournines-slide0-7675998aed.png in stock 364.00 USD FourNines new no Cellular Repair prod_01KPGYRH5HSSV8NY40YECCN4Z2 Selank 45mg Nasal Spray — FourNines Selank is a synthetic heptapeptide developed from the endogenous immunomodulator tuftsin. Research models show it modulates the GABAergic system and influences BDNF expression in specific hippocampal regions. Unlike benzodiazepines, animal studies indicate its anxiolytic profile does not produce sedation, cognitive impairment, or tolerance, making it a notable investigational tool for stress-response research. Research Applications • Anxiolytic pathway research — GABA-A receptor modulation without sedation endpoints. • Neurotrophic factor studies — BDNF/nerve growth factor expression models. • Stress-response investigations — HPA axis regulation in chronic-stress models. • Cognitive performance models — attention and working memory under stress. Preparation Reconstitute the 5mg vial with 1mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 5 IU = 0.05 mL = 250 mcg. Nasal spray presentation (if selected) is pre-calibrated per-actuation. https://lifespansupply.com/product/selank-45mg-nasal-spray-fournines https://api.lifespansupply.com/static/2026-04-18-selank-45mg-nasal-spray-fournines-slide0-0a6df3a8b9.png in stock 243.00 USD FourNines new no Cognitive prod_01KPGYT576TEQHBY8HYGEDA7AC PT-141 10mg — Calyssee PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-MSH that acts primarily at melanocortin receptors MC3R and MC4R. Research models show it modulates central signaling pathways associated with pigmentation, appetite regulation, and autonomic response — distinct from peripherally-acting peptides. Initial development was for sunless tanning; later research focused on CNS-mediated endpoints. Research Applications • Melanocortin pathway research — MC3R/MC4R agonism studies. • Central nervous system signaling — probe for hypothalamic pathways. • Pigmentation biology — MSH-pathway activation studies. • Autonomic response modeling — investigation of sympathetic tone and cardiovascular responses. Preparation For the 10mg vial: reconstitute with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 500 mcg. For nasal spray presentations the device is pre-calibrated — follow the included dosing card. https://lifespansupply.com/product/pt-141-10mg-calyssee https://api.lifespansupply.com/static/2026-04-19-pt-141-10mg-calyssee-slide0-6a3b8e1bcc.png in stock 76.00 USD Calyssee new no Beauty prod_01KPGYT5MCS04B4TCHZK19JHN7 Retatrutide 5mg — Calyssee Retatrutide is a synthetic peptide agonist at three receptors simultaneously: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. Research models demonstrate substantial reductions in body weight and glycemic parameters in obesity and type-2 diabetes investigations, exceeding the effects of dual GIP/GLP-1 agonists. The glucagon component is thought to contribute additional hepatic and energy-expenditure effects. Research Applications • Weight management research — preclinical and translational obesity models. • Glycemic control — GIP/GLP-1 co-agonist pathway studies. • Hepatic lipid metabolism — glucagon-receptor contribution investigations. • Cardiometabolic risk models — integrated metabolic endpoint research. Preparation Reconstitute the 5mg vial with 2mL bacteriostatic water → 2.5 mg/mL. On a U-100 insulin syringe, 8 IU = 0.08 mL = 200 mcg as a starter dose per research protocols. https://lifespansupply.com/product/retatrutide-5mg-calyssee https://api.lifespansupply.com/static/2026-04-19-retatrutide-5mg-calyssee-slide0-7a90e14474.png in stock 258.00 USD Calyssee new no GLP-1 Agonists prod_01KPGYT5Y3YHQYMW771CS2M1Z9 PT-141 150mg Nasal Spray — Calyssee PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-MSH that acts primarily at melanocortin receptors MC3R and MC4R. Research models show it modulates central signaling pathways associated with pigmentation, appetite regulation, and autonomic response — distinct from peripherally-acting peptides. Initial development was for sunless tanning; later research focused on CNS-mediated endpoints. Research Applications • Melanocortin pathway research — MC3R/MC4R agonism studies. • Central nervous system signaling — probe for hypothalamic pathways. • Pigmentation biology — MSH-pathway activation studies. • Autonomic response modeling — investigation of sympathetic tone and cardiovascular responses. Preparation For the 10mg vial: reconstitute with 2mL bacteriostatic water → 5 mg/mL. On a U-100 insulin syringe, 10 IU = 0.1 mL = 500 mcg. For nasal spray presentations the device is pre-calibrated — follow the included dosing card. https://lifespansupply.com/product/pt-141-150mg-nasal-spray-calyssee https://api.lifespansupply.com/static/2026-04-18-pt-141-150mg-nasal-spray-calyssee-slide0-9301f0a1f4.png in stock 152.00 USD Calyssee new no Beauty prod_01KPGYX84KFBB0AHS269ZPBSV9 Wolverine Stack: BPC-157 + Thymosin Beta-4 — Calyssee The Wolverine Stack is a two-peptide research protocol designed for aggressive soft-tissue recovery — pairing BPC-157, the 15-amino-acid pentadecapeptide derived from gastric protective protein, with Thymosin Beta-4, the 43-amino-acid actin-sequestering peptide. Each vial is independently HPLC-verified at ≥99% purity and ships with a full Certificate of Analysis. These two peptides target complementary, non-overlapping pathways in the soft-tissue repair cascade. BPC-157 drives angiogenesis via VEGFR2 signaling and acts locally when injected near the lesion; Thymosin Beta-4 operates systemically, promoting cell migration and endothelial recruitment across multiple tissue compartments. The combination is the most-cited peptide stack in preclinical tendon, ligament, and muscle-belly injury research. Research Applications • Tendon & ligament repair — additive effects across angiogenesis and cell migration axes. • Muscle tissue recovery — post-injury regeneration and reduced scar formation in preclinical models. • Mucosal & gut research — BPC-157 cytoprotection combined with systemic TB4 repair signaling. • Surgical recovery models — investigation of coordinated healing across wound healing phases. Preparation Reconstitute each vial with 2mL bacteriostatic water along the interior wall (never directly into powder). Yields 2.5 mg/mL per vial. On a U-100 insulin syringe, 10 IU = 0.1 mL = 250 mcg. Standard research protocol: BPC-157 250 mcg SC 1–2× daily local to injury; TB4 2.5 mg SC 2–3× weekly systemic. https://lifespansupply.com/product/wolverine-stack-bpc-tb4-calyssee https://api.lifespansupply.com/static/2026-04-19-wolverine-stack-bpc-tb4-calyssee-slide0-22ee624620.png in stock 137.00 USD Supreme Biologics new no Stacks prod_01KPGYXR29MC7DDPFVEV354ZRM GLOW Stack: GHK-Cu + BPC-157 + NAD+ — Calyssee The GLOW Stack is Calyssee's premium three-peptide research protocol covering the full dermal remodelling and cellular energy axis: collagen/elastin synthesis (GHK-Cu), vascular and tissue repair (BPC-157), and mitochondrial NAD+ restoration. Each component is independently HPLC-verified at ≥99% purity, with the NAD+ component presented at 500mg reconstituting in 10ml bacteriostatic water — the same vial footprint as standard 100mg presentations, concentrated for cycle efficiency. The three peptides operate on complementary mechanisms. GHK-Cu delivers copper ions to lysyl oxidase, activating collagen and elastin crosslinking while modulating gene expression through broad transcriptional programs. BPC-157 drives VEGFR2-mediated angiogenesis, supporting the vascular supply that quality dermal remodelling depends on. NAD+ restoration activates sirtuin enzymes (SIRT1/SIRT3), supporting DNA repair and mitochondrial biogenesis — the cellular energy foundation for sustained tissue-remodelling capacity. Research Applications • Dermal anti-aging research — combined collagen synthesis (GHK-Cu) + angiogenic support (BPC-157) + cellular energy (NAD+) for integrated skin-remodelling models. • Post-procedure recovery models — laser, microneedling, chemical peel recovery protocols. • Longevity stack research — three complementary longevity mechanisms in one integrated protocol. • Hair follicle biology — GHK-Cu dermal papilla effects combined with supporting vascular and cellular-energy pathways. Preparation • GHK-Cu 50mg: reconstitute with 5mL bacteriostatic water → 10 mg/mL. Solution will appear blue (copper salt — normal). 10 IU on U-100 = 1 mg. Do NOT freeze reconstituted. • BPC-157 10mg: reconstitute with 2mL bacteriostatic water → 5 mg/mL. 10 IU on U-100 = 500 mcg. • NAD+ 500mg: reconstitute with 10mL bacteriostatic water → 50 mg/mL. 10 IU on U-100 = 5 mg. Slow administration over 10+ minutes to minimize flushing. https://lifespansupply.com/product/glow-stack-ghk-bpc-nad-calyssee https://api.lifespansupply.com/static/2026-04-19-glow-stack-ghk-bpc-nad-calyssee-slide0-e3bbedae4d.png in stock 607.00 USD Calyssee new no Stacks